Table I.

Association analysis of rs7166081 with OA using the arcOGEN data

Stratum	Cases n	Controls n	C-allele frequency cases	C-allele frequency controls	P-value	Odds ratio*
All cases	5804	11,009	0.220	0.235	0.027	0.921 (0.857–0.991)
Hip cases	3039	11,009	0.214	0.233	0.002	0.896 (0.837–0.960)
Knee cases	2164	11,009	0.221	0.233	0.077	0.932 (0.862–1.008)
Female cases	3363	5515	0.217	0.235	0.030	0.904 (0.826–0.991)
Male cases	2441	5494	0.211	0.232	0.020	0.883 (0.794–0.980)
Female hip cases	1769	5515	0.222	0.235	0.183	0.931 (0.838–1.034)
Female knee cases	1217	5515	0.215	0.232	0.014	0.903 (0.832–0.980)
Male hip cases	1270	5494	0.220	0.232	0.232	0.931 (0.828–1.047)
Male knee cases	947	5494	0.218	0.233	0.001	0.915 (0.867–0.965)

^∗(95% confidence intervals).