Table 6.
Results of major IORT series
| Author | Year | n | f/u | R0 (%) | IORT | EBRT | 5-y-LC | 5-y-OS | LP (%) | FC (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Edmonson [13] |
2001 |
39 |
70 |
62 |
10-20 |
45 |
90* |
80 |
95 |
n.r. |
| Azinovic [14] |
2003 |
45 |
93 |
67 |
15 |
45-50 |
80* |
64* |
88 |
77 |
| Kretzler [15] |
2004 |
28 |
52 |
61 |
12-15 |
50 |
84 |
66 |
100 |
59 |
| Llacer [17] |
2006 |
79 |
58 |
42 |
20 (LDR) |
45-50 |
90 |
69 |
100 |
n.r. |
| Oertel [16] |
2006 |
128° |
33 |
49 |
15 |
45 |
83 |
83 |
90 |
86 |
| Alvarez [18] |
2008 |
53 |
66 |
n.r. |
7.5-12.5 |
n.r. |
87 |
75 |
83 |
81 |
| Current Study | 2013 | 34 | 43 | 88 | 10-15 | 40-50 | 97 | 79 | 94 | 81 |
n: number of patients, f/u: median follow up,%: percentage, R0: rate of microscopic complete resections, IORT: intraoperative radiation therapy dose in Gy, EBRT: external beam radiation therapy dose in Gy, 5-y-LC: estimated 5-year-local control rate in%, 5-y-OS: estimated 5-year-overall survival rate in%, LP: limb preservation rate, FC (%): rate of excellent/good functional outcome, *: crude rates, °: excluding patients with distant metastases at time of surgery.