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. Author manuscript; available in PMC: 2015 Jun 1.

Published in final edited form as: Spine J. 2013 Dec 1;14(6):1017–1028. doi: 10.1016/j.spinee.2013.11.034

Representative histological specimens of rats sacrificed at 24 weeks. A) Normal control. B) Disc treated with 5 mg/mL simvastatin. C) Disc treated with 15 mg/mL simvastatin. Note in A and B the regular appearance of the AF, the intact border of the AF and NP, and the increased cellularity compared to C. (Images at 4x microscopic power.)

Representative histological specimens of rats sacrificed at 24 weeks. A) Normal control. B) Disc treated with 5 mg/mL simvastatin. C) Disc treated with 15 mg/mL simvastatin. Note in A and B the regular appearance of the AF, the intact border of the AF and NP, and the increased cellularity compared to C. (Images at 4x microscopic power.)