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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Spine J. 2013 Dec 1;14(6):1017–1028. doi: 10.1016/j.spinee.2013.11.034

Table 3.

Histological grades of disc spaces based on readings of 3 independent observers.

Time (wks) Treatment Groups (Mean ± Standard Deviation)
Normal Control Stab Saline Only Saline + 5 mg/mL Simvastatin Saline + 10 mg/mL Simvastatin Saline + 15 mg/mL Simvastatin Gel Only Gel + 5 mg/mL Simvastatin Gel + 15 mg/mL Simvastatin
2 5.8 ± 1.1 (n = 15) 6.8 ± 1.9 (n = 4) 5.3 ± 1.2 (n = 3) 7.0 ± 0.8 (n = 4) 6.5 ± 1.3 (n = 4) 7.7 ± 3.5 (n = 3) 6.3 ± 2.1 (n = 4) 10.1 ± 3.5 (n = 4)
8 5.7 ± 1.7 (n = 16) 8.0 ± 3.5 (n = 3) 8.3 ± 4.4 (n = 4) 6.0 ± 0.8 (n = 4) 6.3 ± 1.5 (n = 4) 8.8 ± 2.50 (n = 4) 9.8 ± 3.3 (n = 4) 7.7 ± 1.5 (n = 3) 8.3 ± 3.3 (n = 4)
12 5.9 ± 1.6 (n = 12) 9.0 ± 2.7 (n = 3) 6.3 ± 3.9 (n = 4) 10.5 ± 3.0 (n = 4) 9.0 ± 2.9 (n = 4) 5.8 ± 1.0 (n = 4) 6.0 ± 2.3 (n = 4)
24 5.9 ± 1.1 (n = 8) 6.7 ± 2.9 (n = 3) 6.5 ± 1.0 (n = 4) 5.5 ± 0.6 (n = 4) 8.0 ± 2.7 (n = 3)

n = number of disc spaces graded