Table 5.

Gene expression of aggrecan.

Treatment Group	Time Point (Ratio to Control ± Standard Deviation)
	2 Weeks	4 Weeks	8 Weeks	12 Weeks	24 Weeks
Saline only		1.27 ± 0.29			0.20 ± 0.03
Saline + 5 mg/mL simvastatin	2.07 ± 1.35	0.84 ± 0.12	1.33 ± 0.11
Saline + 10 mg/mL simvastatin	1.41 ± 0.33	1.82 ± 0.27	1.57 ± 0.35
Saline + 15 mg/mL simvastatin		2.19 ± 0.47	0.86 ± 0.17	0.70 ± 0.10	2.29 ± 0.29
Hydrogel only			0.83 ± 0.18	1.03 ± 0.14
Hydrogel + 5 mg/mL simvastatin		0.99 ± 0.18	1.85 ± 0.23		1.99 ± 0.48
Hydrogel + 15 mg/mL simvastatin		0.86 ± 0.35	0.97 ± 0.15	2.81 ± 0.17	3.09 ± 1.03