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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Spine J. 2013 Dec 1;14(6):1017–1028. doi: 10.1016/j.spinee.2013.11.034

Table 6.

Gene expression of collagen type II.

Treatment Group Time Point (Ratio to Control ± Standard Deviation)
2 Weeks 4 Weeks 8 Weeks 12 Weeks 24 Weeks
Saline only 0.91 ± 0.20 0.59 ± 0.10
Saline + 5 mg/mL simvastatin 4.10 ± 0.70 1.62 ± 0.34 2.38 ± 1.21
Saline + 10 mg/mL simvastatin 0.77 ± 0.14 3.18 ± 0.45 3.87 ± 0.86
Saline + 15 mg/mL simvastatin 7.43 ± 1.23 0.74 ± 0.15 1.19 ± 0.24 1.78 ± 0.21
Hydrogel only 0.64 ± 0.42 1.67 ± 0.37
Hydrogel + 5 mg/mL simvastatin 3.17 ± 0.59 0.48 ± 0.13 2.25 ± 0.32 0.94 ± 0.44
Hydrogel + 15 mg/mL simvastatin 2.55 ± 0.83 1.59 ± 0.20 11.63 ± 1.55 2.22 ± 0.49