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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Spine J. 2013 Dec 1;14(6):1017–1028. doi: 10.1016/j.spinee.2013.11.034

Table 7.

Gene expression of collagen type I.

Treatment Group Time Point (Ratio to Control ± Standard Deviation)
2 Weeks 4 Weeks 12 Weeks 24 Weeks
Saline only 0.81 ± 0.71 65.80 ± 20.56 3.92 ± 0.70
Saline + 5 mg/mL simvastatin 1.27 ± 0.42 216.09 ± 171.70
Saline + 10 mg/mL simvastatin 3.98 ± 0.84 49.26 ± 14.49
Saline + 15 mg/mL simvastatin 70.99 ± 56.75 28.19 ± 6.97 3.69 ± 0.40
Hydrogel only 4.80 ± 0.72
Hydrogel + 5 mg/mL simvastatin 1.26 ± 0.95 0.17 ± 0.03
Hydrogel + 15 mg/mL simvastatin 1.12 ± 0.89 11.35 ± 9.17 1.84 ± 0.24