Figure 3.

Joint effect of body mass index at age 18 and weight change on healthy survival in the Nurses’ Health Study. Adjusted odds with 95% confidence intervals. Multivariable model adjusted for age (years), education (registered nurse, bachelor, master, or doctoral degree), husband’s education (less than high school, some high school, high school graduate, college graduate, or graduate school), marital status (married, widowed, separated/divorced/never married), postmenopausal hormone use (never used, past user, or current user), smoking status (never smoked, past smoker, current smoker 1–14, 15–24, or ≥25 cigarettes/day), family history of heart disease (yes/no), family history of diabetes (yes/no), family history of cancer (yes/no), vigorous physical activity (hour/week), polyunsaturated–saturated fat ratio (in fifths), intakes of trans fat, alcohol, and cereal fiber (all in fifths), and intakes of fruits and vegetables and red meat (in thirds), all defined at baseline. From Sun Q, Townsend MK, Okereke OI, Franco OH, Hu FB, Grodstein F (2009). Adiposity and weight change in midlife in relation to healthy survival after age 70 in women: prospective cohort study. BMJ. 339, b3796.