Figure 2. Evolutionary conservation of KNL1 domain architecture.

Key KNL1 functional regions are shown for several organisms. The number of amino acids in KNL1 for the various organisms are shown (right). Two values in this column indicate multiple isoforms (H. sapiens). The green region in D. melanogaster indicates the presence of repetitive motifs that differ from the MELT consensus motif observed in other organisms (Schittenhelm et al. 2009).