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. 2014 Apr 18;73(6):1253–1261. doi: 10.1007/s00280-014-2461-5

Table 4.

Reasons for discontinuation during 1–5 courses of treatment (6 months)

Reason for discontinuation Control group Study group
n = 138 % n = 124 %
Severe AEs
 Hematologic toxicity 2 1.4 6 4.8
 Nonhematologic toxicity 30 21.7 20 16.1
 Complication 5 3.6 4 3.2
Patient refusal
 Reasons other than AEs 14 10.1 23 18.5
 Because of AEs 30 21.7 11 8.9
Over rest period 32 23.2 37 29.8
Others 25 18.1 23 18.5