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. 2014 Apr 18;73(6):1253–1261. doi: 10.1007/s00280-014-2461-5

Table 6.

AEs during 6–10 courses of treatment and during 11–15 courses of treatment in the study group

Study group (n = 403) in 6–10 courses Study group (n = 333) in 11–15 courses
Any grade (%) ≥Grade 3 (%) Any grade (%) ≥Grade 3 (%)
Hb 20.8 0.7 17.7 0.0
WBC 13.4 0.0 12.9 0.6
Neut 7.9 0.7 6.0 0.6
Plt 10.2 0.0 10.5 0.3
AST 18.6 0.0 14.7 0.6
ALT 18.6 0.2 12.9 0.6
Al-p 12.7 0.0 13.2 0.3
T-Bil 27.0 0.5 28.8 0.0
BUN 3.2 0.0 4.8 0.0
Creatinine 2.7 0.0 3.6 0.0
Anorexia 8.7 0.5 4.8 0.0
Nausea 4.7 0.0 3.0 0.0
Vomiting 3.2 0.0 0.9 0.0
Stomatitis 7.7 0.0 5.4 0.0
Diarrhea 9.7 0.2 6.6 0.0
Rash 5.0 0.0 3.6 0.0
Hand-foot 9.9 1.0 7.8 0.3
Alopecia 0.7 0.0 0.0 0.0
Fatigue 9.7 0.5 6.6 0.0