Table 2.
Acute toxicities, perioperative complications, and late morbidities in patients with locally advanced rectal cancer.
| Acute toxicities | N = 36 (%) |
|---|---|
| Grade 3 or 4 toxicities | 4 (11.1) |
| Nausea/vomiting | |
| Grade 1 | 5 (13.9) |
| Grade 2 | 1 (2.8) |
| Diarrhea | |
| Grade 1 | 11 (30.6) |
| Grade 2 | 10 (27.8) |
| Grade 3 | 4 (11.1) |
| Leukopenia | |
| Grade 1 | 2 (5.6) |
| Grade 2 | 1 (2.8) |
| Anemia | |
| Grade 2 | 3 (8.3) |
| Frequency/urgency/cystitis | |
| Grade 1 | 6 (16.7) |
| Grade 2 | 3 (8.3) |
| Dermatitis | |
| Grade 1 | 22 (61.1) |
| Grade 2 | 5 (13.9) |
| Hand-foot syndrome | |
| Grade 1 | 1 (2.8) |
| Grade 2 | 1 (2.8) |
|
| |
| Perioperative complications | N = 29 (%) |
|
| |
| Anastomotic leakage (after low anterior resection) | 2 (6.9) |
| Pelvic abscess (after low anterior resection) | 1 (3.4) |
|
| |
| Late morbidities | N = 35 (%) |
|
| |
| Grade ≥ 3 toxicities | 5 (14.3) |
| Colitis | |
| Grade 1 | 3 (8.6) |
| Grade 2 | 2 (5.7) |
| Small bowel obstruction | |
| Grade 2 | 2 (5.7) |
| Grade 3 | 2 (5.7) |
| Anastomotic stenosis | |
| Grade 1 | 1 (2.9) |
| Grade 2 | 4 (11.4) |
| Grade 3 | 1 (2.9) |
| Fistula | |
| Grade 4 | 2 (5.7) |
| Chronic diarrhea | |
| Grade 1 | 4 (11.4) |
| Grade 2 | 2 (5.7) |
| Stool incontinence | |
| Grade 2 | 1 (2.9) |
| Ureter adhesion or stricture | |
| Grade 1 | 4 (11.4) |
| Grade 2 | 3 (8.6) |
| Cystitis and/or hematuria | |
| Grade 1 | 4 (11.4) |
| Grade 2 | 4 (11.4) |