Table 2.
The Health Core Sample with new episodes of CNCP#
| Total Sample | Post-Index Opioid Abuse or Dependence Diagnosis | No Post-Index Opioid Abuse or Dependence Diagnosis | |
|---|---|---|---|
|
| |||
| N=568,640 | N=497 | N=568,143 | |
|
| |||
| N (%) | N (%) | N (%) | |
| Opioid Dose and Days Supply | |||
| No opioid use | 371,371 (65.3) | 150 (30.2) | 371,221 (65.30 |
| Low dose, acute | 90,415 (15.9) | 111 (22.3) | 90,304 (15.9) |
| Low dose, chronic | 6,902 (1.2) | 50 (10.1) | 6,852 (1.2) |
| Medium dose, acute | 83,542 (14.7) | 101 (20.3) | 83,441 (14.7) |
| Medium dose, chronic | 3,654 (0.6) | 47 (9.5) | 3,607 (0.6) |
| High dose, acute | 12,378 (2.2) | 15 (3.0) | 12,363 (2.2) |
| High dose, chronic | 378 (0.1) | 23 (4.6) | 355 (0.1) |
| Age in Years | |||
| 18–30 | 65,089 (11.4) | 156 (31.4) | 64,933 (11.4) |
| 31–40 | 112,412 (19.8) | 126 (25.4) | 112,286 (19.8) |
| 41–50 | 154,635 (27.2) | 123 (24.7) | 154,512 (27.2) |
| 51–64 | 167,558 (29.5) | 82 (16.5) | 167,476 (29.5) |
| >=65 | 68,946 (12.1) | 10 (2.0) | 68,935 (12.1) |
| Gender | |||
| Female | 331,533 (58.3) | 185 (37.2). | 331,348 (58.3) |
| Male | 237,107 (41.7) | 312 (62.8) | 236,795 (41.7) |
| # of types of tracer pains (of 5) in the PRE Index period | |||
| None | 504,208 (88.7) | 448 (90.1) | 503,760 (88.7) |
| One | 58,348 (10.3) | 42 (8.5) | 58,306 (10.3) |
| Two or more | 6,084 (1.1) | 7 (1.4) | 6,077 (1.1) |
| Number of Non-Tracer Pain Categories | |||
| 0 | 363,779 (64.0) | 340 (68.4) | 363,439 (64.0) |
| 1 | 145,825 (25.6) | 105 (21.1) | 145,720 (25.6) |
| 2–3 | 56,423 (9.9) | 47 (9.5) | 56,376 (9.9) |
| 4+ | 2,316 (0.5) | 5 (1.0) | 2,608 (0.5) |
| Number of Non-Substance Mental Health Disorder Types | |||
| 0 | 525,555 (92.4) | 346 (69.6) | 525,209 (92.7) |
| 1 | 36,659(6.4) | 106 (21.3) | 36,553 (6.4) |
| 2+ | 5,426 (1.1) | 45 (9.1) | 6,381 (1.1) |
| Pre-index Substance Abuse/ Dependence Diagnoses | |||
| Opioid | 172 (0.0) | 78 (15.7) | 94 (0.0) |
| Non-Opioid | 605 (0.1) | 51 (10.3) | 554 (0.1) |
| Alcohol | 1,145 (0.2) | 31 (6.2) | 1,114 (0.2) |
| Charlson score - Mean (SD) | 0.16 (0.50) | 0.16 (0.50) | 0.16 (0.50) |
#
All independent variables, except the opioid variables (days supply, dose, category type) were measured in the 12 months prior to the index date. Opioid variables were measured in the 12-month period after the index date.