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Dogs awoke to the conditioned salient stimulus and slept through the neutral stimulus. Percentage of dogs (n = 6–8) aroused into Active Wake during (A) unmedicated (20% Vitamin E TPGS vehicle) night sleep, (B) DORA-22-induced daytime sleep, and (C) DORA-22-induced night sleep with the neutral acoustical stimulus and salient conditioned stimulus (CS). Mean percentage per dog across 2 tests/condition ± SEM. ***p < 0.0001.
