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Electrophysiological effects. Stimulation of CB1 receptors with HU210 caused inhibition of striatal GABAergic sIPSCs in the VHL group. AM251 (alone or with URB597) and haloperidol treatments resulted in the suppression of HU210 effects. CB1 receptor sensitivity was rescued when haloperidol and URB597 were coadministered, although URB597 alone did not increase HU210 effects.
