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. 2014 May 19;7:38. doi: 10.3389/fnmol.2014.00038

Table 1.

Ocular localization of nitric oxide synthase (NOS), soluble guanylate cyclase (sGC), and NP receptors (NPR).

Gene Species Cell- or tissue type References
NOS1 Human Ciliary non-pigmented epithelium Nathanson and Mckee, 1995a
Human ONH astrocytes, lamina cribrosa Neufeld et al., 1997
Monkey Amacrine cells, rod and cone photoreceptors, RGC Haberecht et al., 1998
Canine RGC Franco-Bourland et al., 1998
Rabbit Amacrine cells, rod and cone photoreceptors, RGC Haberecht et al., 1998
Rat Ciliary process epithelium Yamamoto et al., 1993
Murine Retinal amacrine cells May and Mittag, 2004
Murine Retinal amacrine cells, RGC layer somata; IPL puncta Blom et al., 2012
Murine Müller cells Chen et al., 2013
NOS2 Human Macrophages in stroma and ciliary processes Nathanson and Mckee, 1995a
Human Astrocytes Liu and Neufeld, 2001
NOS3 Human Longitudinal CM fibers, TM, SC Nathanson and Mckee, 1995b
Human Retinal vasculature Neufeld et al., 1997
Human TM Fernandez-Durango et al., 2008
sGC Human RGC, IPL, ONL Buys et al., 2013
Human TM cells Ellis et al., 2009
Rabbit Amacrine cells, bipolar cells, cone photoreceptors, RGC Haberecht et al., 1998
Murine Somata in the INL, ONL, IPL, and OPL. Blom et al., 2012
Murine RGC, IPL, ONL Buys et al., 2013
Turtle Amacrine cells; bipolar cells, RGC layer, IPL Blute et al., 1998
NPR Rabbit Ciliary processes Mittag et al., 1987
Rabbit/bovine/human Corneal endothelium Walkenbach et al., 1993
Rabbit/rat Retina, choroid and ciliary process Fernandez-Durango et al., 1995
Human Retina Rollin et al., 2004
Bovine Choroid Schmidt et al., 2004

ONH, optic nerve head; RGC, retinal ganglion cell; IPL, inner plexiform layer; CM, ciliary muscle; TM, trabecular meshwork; SC, Schlemm's canal; ONL, outer nuclear layer; INL, inner nuclear layer; OPL, outer plexiform layer.