Table 3.

The relationship between maternal alcohol intake 4 weeks before pregnancy and size at birth and preterm delivery (n=1152)

	Unadjusted change (95% CI)	p Value*	Adjusted change† (95% CI)	p Value*
Birth weight (g)
Non-drinkers	0.0	0.9	0.0	0.03
≤2 Units/week	−14.6 (−147.4 to 118.1)		−70.2 (−167.4 to 26.9)
>2 Units/week	−23.2 (−123.6 to 77.1)		−105.7 (−183.5 to −27.9)
Customised birth centile‡
Non-drinkers	0.0	0.1	0.0	0.009
≤2 Units/week	−2.8 (−9.4 to 3.9)		−4.2 (−10.9 to 2.4)
>2 Units/week	−4.9 (−9.9 to 0.1)		−7.7 (−12.8 to −2.6)
	Unadjusted OR (95% CI)	p Value*	Adjusted OR† (95% CI)	p Value*
SGA (<10th centile)‡
Non-drinkers	1.0	0.5	1.0	0.2
≤2 Units/week	1.4 (0.7 to 2.7)		1.7 (0.8 to 3.5)
>2 Units/week	1.4 (0.8 to 2.3)		1.8 (0.9 to 3.2)
Low birth weight (≤2500 g)
Non-drinkers	1.0	0.5	1.0	0.4
≤2 Units/week	0.6 (0.2 to 1.7)		0.4 (0.1 to 2.7)
>2 Units/week	0.9 (0.4 to 2.2)		1.1 (0.2 to 6.1)
Preterm birth (<37 weeks gestation)
Non-drinkers	1.0	0.9	1.0	0.5
≤2 Units/week	1.4 (0.7 to 2.7)		1.7 (0.6 to 6.4)
>2 Units/week	1.4 (0.8 to 2.3)		2.0 (0.7 to 6.2)

*p For trend for categories of alcohol intake.

†Adjusted for maternal pre-pregnancy weight, height, age, parity, ethnicity, salivary cotinine levels, caffeine intake, education, energy intake, gestation and baby's sex in a multivariable linear regression for continuous outcomes and a multivariable logistic regression for categorical outcomes.

‡Takes into account maternal pre-pregnancy weight, height, parity, ethnicity, gestation and baby's sex.

SGA, small for gestational age.