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. 2014 Jun;98(Suppl 1):i11–i16. doi: 10.1136/bjophthalmol-2014-305302

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This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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Cell viability assay. (A) No significant decrease in % cell viability was seen in 1/2×, 1×, 2×, 10× ranibizumab-treated ARPE-19 cells, p>0.05. (B) Cell viability decreased to 82% in 10× bevacizumab-treated cells when compared with controls (p=0.0002). No statistically significant change in cell viability was observed on treatment with either 1/2×, 1×, or 2× concentration of bevacizumab. (C) A statistically significant decrease in cell viability (83%) was seen in 10× aflibercept-treated cells (p=0.0001). There was no significant change in 1/2×, 1× and 2× concentrations when compared with controls, p>0.05. (D) Ziv-aflibercept-treated ARPE-19 cells showed a 77% reduction of cell viability at 10 concentration, p<0.0001. No statistically significant change was observed at all other concentrations.