Table 1.
Enzymatic potency of MSC2360844 and MSC2364588 in human class I PI3K isoforms.
| Enzymatic potency IC50 (nM) | ||
|---|---|---|
| Isoform | MSC2360844 | MSC2364588 |
| PI3K δ | 145 | 15 |
| PI3K α | 18,500 | 7,650 |
| PI3K β | 2,850 | 2,450 |
| PI3K γ | >20,000 | >20,000 |
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