Table 5.
Urinary bother in patients with and without late urinary symptom flare following SBRT for prostate cancer (patient-reported responses to question 5 of the EPIC-26.).
| Start | 1 Month | 3 Months | 6 Months | 9 Months | 12 Months | 18 Months | 24 Months | |
|---|---|---|---|---|---|---|---|---|
| ALL PATIENTS | ||||||||
| N | 214 | 211 | 208 | 198 | 197 | 196 | 182 | 196 |
| No problem (%) | 46.3 | 24.6 | 40.9 | 42.9 | 40.1 | 35.7 | 44.5 | 45.4 |
| Very small–small problem (%) | 44.4 | 57.8 | 50.5 | 48.0 | 44.2 | 49.5 | 41.8 | 45.9 |
| Moderate–big problem (%) | 9.3 | 17.5 | 8.7 | 9.1 | 15.7 | 14.8 | 13.7 | 8.7 |
| p-Value | <0.0001* | 0.9201 | 0.7601 | 0.0777 | 0.0086* | 0.4353 | 0.7329 | |
| PATIENTS WITHOUT FLARE | ||||||||
| N | 185 | 184 | 180 | 172 | 169 | 168 | 155 | 170 |
| No problem (%) | 43.8 | 24.5 | 42.2 | 44.8 | 43.2 | 38.1 | 46.5 | 45.9 |
| Very small–small problem (%) | 47.6 | 58.2 | 48.9 | 46.5 | 43.2 | 51.8 | 41.3 | 45.9 |
| Moderate–big problem (%) | 8.6 | 17.4 | 8.9 | 8.7 | 13.6 | 10.1 | 12.3 | 8.2 |
| p-Value | <0.0001* | 0.7298 | 0.9282 | 0.5778 | 0.3185 | 0.6496 | 0.3608 | |
| PATIENTS WITH FLARE | ||||||||
| N | 29 | 27 | 28 | 26 | 28 | 28 | 27 | 26 |
| No problem (%) | 62.1 | 25.9 | 32.1 | 30.8 | 21.4 | 21.4 | 33.3 | 42.3 |
| Very small–small problem (%) | 24.1 | 55.6 | 60.7 | 57.7 | 50.0 | 35.7 | 44.4 | 46.2 |
| Moderate–big problem (%) | 13.8 | 18.5 | 7.1 | 11.5 | 28.6 | 42.9 | 22.2 | 11.5 |
| p-Value | 0.0483* | 0.5614 | 0.4307 | 0.0056* | 0.0008* | 0.0737 | 0.3028 | |
*Changes in survey scores that are both statistically and clinically significant.