Table 3.
Multivariate-adjusted regression analyses of plasma Angpt2 and PWV
| Analysis | PWV | ||
|---|---|---|---|
| Regression Coefficient β (×10−5) | P Value | 95% Confidence Interval (×10−5) | |
| Univariate | |||
| Angpt2 | 1.65 | <0.001 | 0.87 to 2.4 |
| Multivariate | |||
| Model 1 | 1.25 | 0.001 | 0.54 to 1.96 |
| Model 2 | 0.96 | 0.01 | 0.25 to 1.67 |
| Model 3 | 0.86 | 0.02 | 0.12 to 1.61 |
PWV was log-transformed. Model 1, is adjusted for Angpt2 plus age. Model 2 is adjusted for the variables in model 1 plus traditional risk (e.g., age, sex, hypertension, diabetes, smoking, dyslipidemia); Model 3 is adjusted for the variables in model 2 plus nontraditional risk factors (e.g., calcium phosphate product, medications including ACE inhibitor, ARB, statin, calcium channel blocker, β-blocker).