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. 2014 Feb 7;25(6):1313–1320. doi: 10.1681/ASN.2013080860

Table 2.

Association between sTNFRs and CKD stages according to the GFR strata in the Kidney Disease Improving Global Outcomes guidelines

CKD Stage eGFR (ml/min per 1.73 m2) ULSAM PIVUS
Participants (n) Mean sTNFR1±SD Participants (n) Mean sTNFR1±SD Mean sTNFR2±SD
G1: Normal or high ≥90 108 1613±507 87 1812±356 4993±3551
G2: Mildly decreased 60–89 511 1973±641 450 2186±449 5727±1692
G3a–b: Mildly to severely decreased 30–60 147 2546±834 262 2924±1425 7412±2492
G4: Severely decreased 15–29 11 5504±2315 10 4343±995 10,107±2088
G5: Kidney failure 0–14 0 0
ANOVA P value <0.001 <0.001 <0.001