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. 2014 May 6;2014:195290. doi: 10.1155/2014/195290

Figure 3.

Figure 3

Anti-ICAM-1 antibody attenuated sepsis-induced lung injury as demonstrated by histopathological tests and wet-to-dry weight ratio. (a) The lungs of the anti-ICAM-1 antibody treated CLP mice, isotype antibody treated CLP mice, saline treated CLP mice, and sham-operated mice were harvested 24 h after surgery for histopathological staining. Histopathological tests showed milder impairment in lungs in anti-ICAM-1 group than in isotype and CLP groups. n = 6 per each group. (b) Lung wet-to-dry weight ratio was reduced in anti-ICAM-1 group than in isotype and saline groups.  *P < 0.05 when anti-ICAM-1 antibody treated mice were compared with mice treated with isotype antibody or saline. Bars represent the mean ± SD.