Table 1.
Characteristics of studies using radiofrequency ablation as a pretransplantation bridge therapy
| Ref. | n | Tumor size (cm) | RFA→LT interval (mo) | Dropout | Radiologic response necrosis | Pathologic response necrosis | Satellites found in explants | Follow-up after LT (mo) |
Survival |
|
| 1-yr | 3-yr | |||||||||
| Pulvirenti et al[34] | 14 | 3.50 | 8.0 | 0.0% | 90.7% | 86.4% | 57.0% | 16.0 | 100.0% | 100.0% |
| Fontana et al[35] | 33 | 3.60 | 7.9 | 21.7% | 66.0% | - | - | 26.9 | 85.0% | 85.0% |
| Mazzaferro et al[36] | 50 | 2.75 | 9.5 | 0.0% | 70.0% | 55.0% | 28.0% | 22.0 | 95.0% | 83.0% |
| Pompili et al[37] | 40 | 2.80 | 8.6 | 0.0% | 75.0% | 46.7% | 14.0% | 34.4 | 91.9% | 85.4% |
| Lu et al[38] | 52 | 2.50 | 8.7 | 5.8% | 89.6% | 70.3% | 24.0% | 14.9 | 85.0% | 76.0% |
| Brillet et al[39] | 21 | 2.40 | 11.9 | 24.0% | 76.0% | 75.0% | 44.0% | 25.0 | - | - |
| DuBay et al[40] | 77 | 2.50 | 9.5 | 21.0% | 83.0% | - | - | 30.0 | -1 | -1 |
1
No significant difference compared with untreated groups. LT: Liver transplantation; RFA: Radiofrequency ablation.