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Recommendations for the use of pegylated interferon as initial antiviral therapy
| HBV genotype | General recommendations for HBeAg positive patients |
| A | Either high ALT (≥ 2 × ULN) or low HBV DNA levels (< 9 log10 copies/mL) |
| B and C | Both high ALT (≥ 2 × ULN) and low HBV DNA levels (< 9 log10 copies/mL) |
| D | Not recommended |
HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen; ALT: Alanine transaminase; ULN: Upper limit of normal.
