Table 9.
Phase | Trial identifier | Design | Drugs | Enrollment | Expected end date |
I | NCT01872065 | Double-blind, randomized | ARC520 | 44 | October 2013 |
NCT01590641 | Double-blind, randomized | GS-9620 | 48 | September 2013 | |
II | NCT00524173 | Open-label, randomized | TDF vs TDF + emtricitabine | 100 | January 2015 |
NCT01204762 | Double-blind, randomized | IFN-λ + ETV | 170 | July 2017 | |
NCT01242787 | Open-label, randomized | LB80380 | 115 | September 2012 | |
III | NCT01595685 | Open-label, randomized | TBV vs ETV | 184 | December 2014 |
NCT01369199 | Open-label, randomized | 8 wk ETV followed by 40 wkPEG-IFN-α-2a + ETV | 250 | May 2016 | |
IV | NCT01804387 | Open-label, randomized | TBV + ADV vs LAM + ADV | 60 | May 2014 |
NCT01906580 | Open-label, randomized | PEG-IFN-α-2a vs ETV | 105 | July 2014 |
Full details of the clinical trials may be found on the United States National Institutes of Health. Available from: URL: http://www.clinicaltrials.gov. LAM: Lamivudine; ETV: Entecavir; ADV: Adefovir; TBV: Telbivudine; TDF: Tenofovir disoproxil fumarate; PEG-IFN: Pegylated interferon.