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. 2014 May 7;2014:657953. doi: 10.1155/2014/657953

Table 4.

Prognostic factors.

Variables Bivariate analyses Multivariate analyses
HR (95% CI) P value HR (95% CI) P value
Age 1.04 (1.01–1.05) P < 0.001 Not significant
KPS (≤80 versus >80) 2.59 (1.55–4.3) P < 0.001 2.08 (0.28–0.83) P = 0.008
RPA
 IV versus III 2.39 (1.18–4.82) P = 0.015 3.46 (1.61–7.46) P = 0.001
 V versus III 6.32 (2.82–14.14) P < 0.001 7.29 (3.23–16.34) P < 0.001
Histology (GBM versus AA) 2.45 (1.53–3.94) P < 0.001 3.13 (1.79–5.48) P < 0.001
Tumour volume    1.04 (1.01–1.07) P = 0.005  Not significant
Treatment volume 1.03 (1.01–1.06) P = 0.013
Margin to PTV
 0 versus ≥1 0.77 (0.67–0.87) P < 0.001 3.19 (1.91–5.31) P < 0.001

*This variable was not considered for the multivariate analyses because of the strong correlation (0.97 Spearman' s correlation coefficient) with tumour volume.