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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Innate Immun. 2013 Nov 26;21(1):99–112. doi: 10.1177/1753425913513815

Figure 1.

Figure 1

Relationship between inflammation, DC activation and HIV infection. Inflammation and DC activation can increase the risk of HIV transmission, while HIV acquisition by DC can also lead to DC activation and inflammation. DCs acquire HIV and can either become infected or transfer the virus to T cells, which become infected. Inflammation can enhance HIV replication in infected cells. Anti-inflammatory mediators can be used to reduce inflammation and DC activation, which lead to a decrease in risk of HIV transmission.