Table 3.
Multivariable analyses evaluating NAC as a predictor of complications
| Outcome | Independent Variable | Multivariable Adjusted OR1 (95% CI) | p-value |
|---|---|---|---|
| Model 1: Any complication | NAC (ref: no NAC) | 0.96 (0.57,1.61) | 0.87 |
| Age (per 10 year increase) | 1.20 (1.03, 1.40) | 0.0186 | |
| Year of operation (2005–2009, ref: 2010–2011) | 0.47 (0.34, 0.65) | <0.0001 | |
| Operative time (per 1 hour increase) | 1.09 (1.01, 1.17) | 0.0345 | |
| Prior surgery within 30 days (ref: no surgery) | 0.47 (0.26, 0.87) | 0.016 | |
| Model 2: Re-operation | NAC (ref: no NAC) | 0.24 (0.03,1.79) | 0.16 |
| Year of operation (2005–2009, ref: 2010–2011) | 2.13 (1.15, 4.0) | 0.02 | |
| More than 2 alcoholic drink in the 2 weeks prior to admission (ref: < 2 drinks) | 3.20 (1.16, 8.85) | 0.03 | |
| Pre-operative acute renal failure (ref: no pre-operative acute renal failure) | 5.89 (1.04, 33.24) | 0.04 | |
| Model 3: Wound/organ space infection * | NAC (ref: no NAC) | 0.67 (0.30,1.49) | 0.32 |
| Model 4: Wound dehiscence | NAC (ref: no NAC) | 0.25 (0.02,3.90) | 0.32 |
| Male sex (ref: no NAC) | 16.51 (1.13, 241.34) | 0.04 | |
| 1 or more pulmonary comorbidities (ref: no pulmonary comorbidities) | 3.49 (1.50, 8.13) | 0.004 | |
| ASA score 4 (ref: 1) | 0.01 (<0.001, 0.31) | 0.008 | |
| ASA score 3 (ref: 1) | 0.06 (0.01, 0.35) | 0.002 | |
| ASA score 2 (ref: 1) | 0.036 (0.01, 0.25) | 0.001 |
*
No significant predictors were noted for this model