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. Author manuscript; available in PMC: 2014 May 27.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Sep 8;(9):CD007855. doi: 10.1002/14651858.CD007855.pub2
Methods RCT.
Participants 47 women included in the analysis.
Women who attended out patient clinics in 2 hospitals (Northwick Park Hospital and Aberdeen) who had bacteriuria of urine obtained through suprapubic aspiration or catheterization
Interventions Group 1: three-day course of cephalexin 1 gram twice a day (23 women)
Group 2: three-day course of pivmecillinam 200 mg and pivampicillin 250 mg (Miraxid®) twice daily (24 women)
Outcomes Primary outcomes:
Symptomatic infection: not reported.
Persistent infection: group 1: 1/23; group 2: 6/24.
Recurrent infection: group 1: 5/23; group 2: 4/24.
Shift to another antibiotic: not reported.
Adverse effects: not reported.
Secondary outcomes:
Preterm delivery: not reported.
Preterm labor: not reported.
Neonatal infection: not reported.
RDS in the neonate: not reported.
Admission to NICU: not reported.
Duration of neonatal respiratory support: not reported.
Notes
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Unclear Not mentioned.
Allocation concealment? Unclear Not mentioned.
Blinding?
Participant
Yes Described as double blind.
Blinding?
Clinician
Yes Described as double blind.
Blinding?
Outcome assessor
No
Incomplete outcome data addressed?
All outcomes
Yes Follow up described as complete.
Free of selective reporting? Yes Planned outcome to be analyzed were all reported.
Free of other bias? Yes