Methods | RCT. | |
Participants | 47 women included in the analysis. Women who attended out patient clinics in 2 hospitals (Northwick Park Hospital and Aberdeen) who had bacteriuria of urine obtained through suprapubic aspiration or catheterization |
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Interventions | Group 1: three-day course of cephalexin 1 gram twice a day (23 women) Group 2: three-day course of pivmecillinam 200 mg and pivampicillin 250 mg (Miraxid®) twice daily (24 women) |
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Outcomes | Primary outcomes: Symptomatic infection: not reported. Persistent infection: group 1: 1/23; group 2: 6/24. Recurrent infection: group 1: 5/23; group 2: 4/24. Shift to another antibiotic: not reported. Adverse effects: not reported. Secondary outcomes: Preterm delivery: not reported. Preterm labor: not reported. Neonatal infection: not reported. RDS in the neonate: not reported. Admission to NICU: not reported. Duration of neonatal respiratory support: not reported. |
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Notes | ||
Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Unclear | Not mentioned. |
Allocation concealment? | Unclear | Not mentioned. |
Blinding? Participant |
Yes | Described as double blind. |
Blinding? Clinician |
Yes | Described as double blind. |
Blinding? Outcome assessor |
No | |
Incomplete outcome data addressed? All outcomes |
Yes | Follow up described as complete. |
Free of selective reporting? | Yes | Planned outcome to be analyzed were all reported. |
Free of other bias? | Yes |