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. 2014 May 26;205(4):447–455. doi: 10.1083/jcb.201312029

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© 2014 Benkemoun et al.

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Figure 2. — Depleting regulators of DNA replication initiation suppresses the asynchrony duration defect of par-4 and par-1 embryos, independently of checkpoint activity. (A and B) Graphs reporting the measurement of asynchrony duration (in seconds) after depletion of regulators of DNA replication initiation (A) or checkpoint regulators (B) in the specified genetic backgrounds. Measurements were made at 18°C for wild-type and par-4(it47ts) embryos and 22°C for par-1(zu310ts) embryos. Empty vector was used for control (Ctl) RNAi. Error bars represent standard deviations, and an asterisk denotes that the value is significantly different from the ctl(RNAi) in the same genetic background (P < 0.05, Student’s t test). The number of embryos analyzed for each condition is indicated. WT, wild type.