Participants |
Requiring terminal care: treatment = 186 (87% with a diagnosis of cancer); control = 43 (86% with a diagnosis of cancer) |
|
Living alone: treatment 21%, control 17% |
|
Mean age: treatment 72 (SD 11); control 73 (SD 14) |
|
Male 50%, female 54% |
|
Survival from referral for both groups a median of 11 days |
|
Interventions |
Referred from primary or secondary care |
|
6 qualified nurses, 2 nursing aides, a co-ordinator (RGN level), agency staff providing 24-hour care if required for a maximum of 2 weeks, most had Marie Curie experience. Intervention patients could also access standard care |
|
Control group received standard care: hospital care or hospice care, with input from the GP and district nurses, Marie Curie nursing, Macmillan nursing, social services and private nursing |
|
Outcomes |
Symptoms and support, GP visits, place of death and admission to hospital |
|
Notes |
UK study |
|
Risk of bias
|
|
Bias
|
Authors’ judgement
|
Support for judgement
|
|
Random sequence generation (selection bias) |
Low risk |
4:1 randomisation ratio (HAH:control) to ensure sufficient admissions to hospital at home. Random numbers from a random number table were used |
|
Allocation concealment (selection bias) |
Low risk |
Allocation for each referral was assigned from a random number table by the researcher and concealed in sequentially numbered, opaque sealed envelopes |
|
Blinding (performance bias and detection bias) |
High risk |
|
All outcomes |
|
|
|
Incomplete outcome data (attrition bias) |
Low risk |
Response rates: 144/198 (73%) for carers, 225/228 (99%) district nurses, 194/228 (85%) primary care physicians |
All outcomes |
|
|
Selective reporting (reporting bias) |
Low risk |
All stated outcomes reported |
|
Baseline measures |
Low risk |
Demographic data |
|
Protection against contamination |
High risk |
Intervention was contaminated by other input available to the control group (e.g. supplemented by GP and other community care when less than 24-hour hospital at home input was provided) |