Table 2.
1-Year follow-up hypoglycemia
| Cohort 1 | Cohort 2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| IMPACT® | Humana® | ||||||||
| DET-S | GLA-C | P | DET-S | GLA-C | P | GLA-S | DET-C | P | |
| n = 536 | n = 2,668 | n = 256 | n = 1,262 | n = 419 | n = 780 | ||||
| Hypoglycemia, n (%) | 65 (12.1) | 296 (11.1) | 0.4903 | 27 (10.5) | 199 (15.8) | 0.0324 | 44 (10.5) | 79 (10.1) | 0.8392 |
| Inpatient/ED hypoglycemia, n (%) | 22 (4.1) | 125 (4.7) | 0.5576 | 14 (5.5) | 103 (8.2) | 0.1408 | 12 (2.9) | 36 (4.6) | 0.1402 |
| Number of hypoglycemia per patient year, mean (SD) | 0.37 (2.39) | 0.30 (1.63) | 0.5041 | 0.41 (2.10) | 0.37 (1.68) | 0.8222 | 0.21 (0.81) | 0.26 (1.75) | 0.4764 |
| Number of inpatient/ED hypoglycemia per patient year, mean (SD) | 0.06 (0.34) | 0.06 (0.35) | 0.9773 | 0.07 (0.37) | 0.12 (0.52) | 0.0739 | 0.04 (0.26) | 0.05 (0.26) | 0.3209 |
DET-C patients continuing on insulin detemir, DET-S patients switching from insulin glargine to insulin detemir, ED emergency department, GLA-C patients continuing on insulin glargine, GLA-S patients switching from insulin detemir to insulin glargine, SD standard deviation