Table 1.
Na channel | CBZ |
FBM | |
LAC | |
LTG | |
OXC | |
PHT | |
RUF | |
TPM | |
VPA | |
ZNS | |
Ca channel | ESX (low voltage T-type) |
GBP (high voltage) | |
LTG (high voltage N-type) | |
OXC | |
PGB (high voltage) | |
PB | |
PHT | |
TPM (high voltage L-type) | |
VPA (low voltage T-type) | |
ZNS (high voltage T-type) | |
GABA enhancers | Benzodiazepines |
PB | |
CBZ | |
GBP | |
PGB | |
TGB (GABA uptake inhibitor) | |
TPM | |
VIG (GABA transaminase inhibitor) | |
VPA | |
Glutamate antagonists | CBZ |
FBM | |
OXC | |
PB | |
TPM | |
Carbonic anhydrase inhibitors | TPM |
ZNS | |
Other | CBZ (adenosine receptor binding) |
LAC (collapsin responsive mediator protein-2) | |
LEV (synaptic protein SV2A binding) | |
PHT (inhibit neurotransmitter release) |
Abbreviations: CBZ: carbamazepine; ESX: ethosuximide; FBM: felbamate; GBP: gabapentin; LEV: levetiracetam; LTG: lamotrigine; OXC: oxcarbazepine; PB: Phenobarbital; PHT: phenytoin; RUF: rufinamide; TGB: tiagabine; TPM: topiramate; VIG: vigabatrin; VPA: valproic acid.