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Characterization of TMV particles. (A) MALDI-TOF MS spectra of the subunit protein of wild type TMV (17534 m/z), TMV-alkyne (17664 m/z), and the CuAAC reaction product TMV-RGD (18503 m/z). The numbers in parentheses refer to the theoretical masses. (B) The morphology of TMV particles before (TMV) and after (TMV-RGD) bioconjugation visualized by AFM and TEM (insets). Scan areas of AFM are 5 × 5 μm; and scale bars of TEM are 200 nm.
