Table A2.
Genes upregulated in HCV monoinfected subjects.
| Gene ID | Name | Short name | Function |
|---|---|---|---|
| 202859_x_at | Interleukin 8 | IL8 | Chemotactic factor that attracts neutrophils, basophils, and T-cells and is involved in neutrophil activation |
| 204103_at | Chemokine (C-C motif) ligand 4 | CCL4 | Monokine involved in cellular adhesion, signaling, and chemotaxis. Attracts NK cells and monocytes |
| 204440_at | CD83 molecule | CD83 | Surface marker for fully mature DC. Important for CD4(+) T cell development in the thymus |
| 204470_at | Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | CXCL1 | Chemotactic activity for neutrophils |
| 205067_at | Interleukin 1, beta | IL1B | Produced by activated macrophages. Stimulates B-cell maturation and proliferation |
| 205114_s_at | Chemokine (C-C motif) ligand 3 /// chemokine (C-C motif) ligand 3-like 1 /// che | CCL3 /// CCL3L1 /// CCL3L3 /// LOC728830 /// LOC730422 | Monokine with inflammatory and chemokinetic properties |
| 205207_at | Interleukin 6 (interferon, beta 2) | IL6 | Cytokine that functions in inflammation and maturation of B lymphocytes |
| 205476_at | Chemokine (C-C motif) ligand 20 | CCL20 | Chemotactic factor that attracts lymphocytes |
| 207850_at | Chemokine (C-X-C motif) ligand 3 | CXCL3 | Chemotactic activity for neutrophils |
| 209774_x_at | Chemokine (C-X-C motif) ligand 2 | CXCL2 | Chemokine produced by activated monocytes and neutrophils and expressed at sites of inflammation |
| 210118_s_at | Interleukin 1, alpha | IL1A | Produced by activated macrophages and stimulates B cell maturation and proliferation |
| 212657_s_at | Interleukin 1 receptor antagonist | IL1RN | Inhibits the activity of IL1 |
| 39402_at | Interleukin 1, beta | IL1B | Produced by activated macrophages and stimulates B cell maturation and proliferation |
| 201925_s_at | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | CD55 | Integral membrane protein of erythrocytes, involved in regulation of complement activation |
| 202643_s_at | Tumor necrosis factor, alpha-induced protein 3 | TNFAIP3 | Involved in immune and inflammatory responses signaled by cytokines through inhibition of NF-kappaB pathway |
| 206359_at | Suppressor of cytokine signaling 3 | SOCS3 | Negative regulator of apoptotic processes and the insulin receptor signaling pathway |
| 207008_at | Interleukin 8 receptor, beta | IL8RB | Activation of neutrophils |
| 207535_s_at | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | NFKB2 | Transcription factor involved in immune and inflammatory pathways, cellular proliferation, cellular differentiation, and apoptosis |
| 209795_at | CD69 molecule | CD69 | Involved in lymphocyte proliferation |
| 210354_at | Interferon, gamma | IFNG | Antiviral activity and several immunoregulatory functions |
| 214637_at | Oncostatin M | OSM | Cytokine that regulates growth and is involved in hepatocyte differentiation |