Table A3.
Genes up regulated in all HCV vasculitis subjects compared to others.
| Gene ID | Name | Short name | Function |
|---|---|---|---|
| 201666_at | TIMP metallopeptidase inhibitor 1 | TIMP1 | Inhibitor of metalloproteinases that degrade extracellular matrix |
| 205321_at | Eukaryotic translation initiation factor 2, subunit 3 gamma, 52 kDa | EIF2S3 | Regulates rate of protein translation |
| 205660_at | 2′-5′-Oligoadenylate synthetase-like protein | OASL | IFN-induced cellular protein that inhibits viral replication of HCV and EMCV |
| 217523_at | CD44 molecule (Indian blood group) | CD44 | Mediates cell-to-cell and cell-to-matrix interactions. Involved in cellular migration and lymphocyte activation |
| 223454_at | Chemokine (C-X-C motif) ligand 16 | CXCL16 | Transmembrane chemokine that promotes cell growth and migration, and involved in chemotaxis of T and NKT cells |
| 224572_s_at | Interferon regulatory factor 2 binding protein 2 | IRF2BP2 | IRF-2 dependent transcriptional co-repressor of type I IFN genes and many IFN-stimulated genes |
| 1554999_at | RasGEF domain family, member 1B | RASGEF1B | Regulation of small GTPase mediated signal transduction |