Fig. 1.

Cardiorespiratory parameters, temperature, and symptoms during experimental endotoxemia in control and trained subjects. (A) Carbon dioxide partial pressure (pCO₂) in arterial blood. (B) Oxygen partial pressure (pO₂) in arterial blood. (C) pH in arterial blood. (D) Bicarbonate (HCO3⁻) in arterial blood. (E) Lactate in arterial blood. (F) Oxygen saturation measured by pulse oximetry. (G) Heart rate (HR). (H) Mean arterial pressure (MAP). (I) Temperature. (J) Score of self-reported symptoms. Data are expressed as mean ± SEM of 12 subjects per group. Gray box indicates period in which the trained subjects practiced their learned breathing techniques. P values between groups were calculated using repeated measures two-way analysis of variance (ANOVA, interaction term). AU, arbitrary units; bpm, beats per minute.