Fig. 4.
The postnatal NG2 progenitor cells found in CC came from SVZ GFAP+ progenitor source. (A) Immunostaining of β-gal and GFAP in Ng2-Cre/Rosa26LacZ double-transgenic mouse brain sections showed that GFAP+ astrocytes in CC are not derived from NG2 progenitors. (B) Immunostaining of β-gal and NG2 in Gfap-Cre/Rosa26LacZ double-transgenic mouse brain sections showed that NG2+ cells within CC were derived from GFAP+ postnatal NPCs. (C) The schematic order of lineage differentiation from GFAP+ NPCs to NG2+ OPCs to myelinating OLs.