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. 2009 Apr 24;42(3):404–411. doi: 10.1111/j.1365-2184.2009.00606.x

Figure 2.

Figure 2

Arsenic trioxide (As2O3) inhibits paclitaxel‐induced mitotic arrest. (a) HeLa cells treated with or without 10 nm paclitaxel and/or 5 µm As(III) for 16 h were stained with the antibody to phorphorylated histone H3 (p‐histone H3, green), DAPI (blue) stained DNA. Representative cell images shown. (b) HeLa cells treated with or without 10 nm paclitaxel and/or 5 µm As(III) for 16 h were fixed and labelled with the antibody to p‐histone H3 for flow cytometry analysis. (c) Flow cytometry data as shown in B were quantified from three independent experiments.