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. Author manuscript; available in PMC: 2014 May 27.
Published in final edited form as: Chem Biol Interact. 2010 Jan 28;184(0):273–278. doi: 10.1016/j.cbi.2010.01.031

Figure 2. Correlation Plot of Gene Expression Profiles as a Function of N-OH-PhIP Dose.

Figure 2

Gene expression analyses were performed in duplicate at the indicated doses of N-hydroxy-PhIP using Affymetrix GeneChip Human Genome U133 Plus™ arrays. After normalization and background subtraction, the similarity in gene expression patterns between all samples was evaluated pair-wise using the Array Assist software package. The heat map in the legend indicates the relationship between color and the correlation coefficient across all genes of a given pair of arrays. Circle highlights a region which illustrates that a dose of 10-6 yields a pattern of gene expression that is substantially different from controls and lower doses.