Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 May 27;8:129. doi: 10.3389/fnins.2014.00129

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Blednov, Benavidez, Black and Harris.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

PDE4 inhibitors reduce alcohol intake during the first 6 h of the 24-h two-bottle choice paradigm. Ethanol consumption is presented as g/kg/6 h: (A) Rolipram (D) Mesopram (G) CDP840 (J) Piclamilast. Preference for ethanol: (B) Rolipram (E) Mesopram (H) CDP840 (K) Piclamilast. Total fluid intake (g/kg/6 h): (C) Rolipram (F) Mesopram (I) CDP840 (L) Piclamilast. Data were analyzed by Two-Way ANOVA with repeated measures followed by Bonferroni's test for multiple comparisons. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001 compared to control (n = 6 per group; EtOH = ethanol).