Table 1.

KEGG pathway enrichment analysis

ID	KEGG pathway	Number of genes	Number of genes in pathway	P-value	FDRa
hsa05200	Pathways in cancer	158	327	5.74 × 10–48	1.11 × 10–45
hsa05215	Prostate cancer	59	89	8.83 × 10–28	8.57 × 10–26
hsa05219	Bladder cancer	33	42	9.62 × 10–20	6.22 × 10–18
hsa05212	Pancreatic cancer	44	70	1.30 × 10–19	6.31 × 10–18
hsa04510	Focal adhesion	82	200	4.58 × 10–19	1.78 × 10–17
hsa05222	Small-cell lung cancer	46	85	8.39 × 10–17	2.62 × 10–15
hsa05220	Chronic myeloid leukemia	42	73	9.45 × 10–17	2.62 × 10–15
hsa05210	Colorectal cancer	38	62	1.46 × 10–16	3.55 × 10–15
hsa04110	Cell cycle	58	128	3.74 × 10–16	8.07 × 10–15
hsa04350	TGF-beta signaling pathway	44	85	3.55 × 10–15	6.89 × 10–14
hsa05223	Non-small-cell lung cancer	33	54	1.72 × 10–14	3.04 × 10–13
hsa04115	p53 signaling pathway	38	69	2.01 × 10–14	3.25 × 10–13
hsa04210	Apoptosis	44	89	3.12 × 10–14	4.66 × 10–13
hsa05214	Glioma	36	65	7.85 × 10–14	1.09 × 10–12
hsa05213	Endometrial cancer	31	52	2.86 × 10–13	3.70 × 10–12
hsa05218	Melanoma	37	71	4.46 × 10–13	5.41 × 10–12
hsa05142	Chagas’ disease (American trypanosomiasis)	46	104	1.37 × 10–11	1.57 × 10–11
hsa05221	Acute myeloid leukemia	31	58	1.53 × 10–11	1.65 × 10–10
hsa04380	Osteoclast differentiation	50	128	4.04 × 10–11	4.12 × 10–10
hsa04012	ErbB signaling pathway	39	87	4.39 × 10–11	4.26 × 10–10

The table shows the results of the hypergeometric test of KEGG pathways.

^aFDR, false discovery rate.