Table 1.
Source reconstruction method details for all localization accuracy comparisons.
| Software package | MEG signal | Source space configuration (vertex spacing) | HPI-MRI co-registration algorithm | MEG reconstruction algorithm | Time window | Statistical comparison | Mean V1, V2, and V3 localization accuracy % (quadrants) |
|---|---|---|---|---|---|---|---|
| MNE | Early evoked response | Individual's cortical surface mesh (3.1–4.9 mm) | Iterative closest point (ICP) | MNE | 20 ms, centered on FRP | dSPM F statistic, 500 ms baseline (previous stimulus) | 77.9 (mean SD: 24.7) |
| OSL | Early evoked response | Brain volume (4 mm) | Iterative closest point (ICP) | Beamformer (1–40 Hz) | 20 ms, centered on FRP | t-test of trial-wise difference between stimuli | 69.1 (mean SD: 36.5) |
| OSL | Stimulus frequency tag (8 Hz) | Brain volume (4 mm) | Iterative closest point (ICP) | Beamformer (7–9 Hz) | 200–1000 ms post stimulus onset | t-test of trial-wise difference between stimuli | 66.0 (mean SD: 39.3) |
| SPM8 | Early evoked response | Inverse-normalized cortical surface mesh (4.9 mm) | Iterative closest point (ICP) | MSP | 40 ms*, centered on FRP | t-test of trial-wise difference between stimuli | 54.9 (mean SD: 33.8) |
| SPM8 | Early evoked response | Inverse-normalized cortical surface mesh (4.9 mm) | Iterative closest point (ICP) | IID | 40 ms*, centered on FRP | t-test of trial-wise difference between stimuli | 57.3 (mean SD: 28.5) |
| SPM8 | Early evoked response | Inverse-normalized cortical surface mesh (4.9 mm) | Iterative closest point (ICP) | MSP | 50–200* ms post stimulus onset | t-test of trial-wise difference between stimuli | 36.9 (mean SD: 25.6) |
| SPM8 | Early evoked response | Inverse-normalized cortical surface mesh (4.9 mm) | Iterative closest point (ICP) | IID | 50–200* ms post stimulus onset | t-test of trial-wise difference between stimuli | 54.8 (mean SD: 38.5) |
*
Gaussian-weighted average over the time period.