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. Author manuscript; available in PMC: 2014 May 27.
Published in final edited form as: Ann Neurol. 2009 Dec;66(6):792–798. doi: 10.1002/ana.21780

Table 1. Description of Significant Genes Identified by Whole Genome Expression.

Symbol Definition Fold change p-Value KEGG pathway/reactome event Biological process
MTND2 Homo sapiens NADH dehydrogenase, subunit 2 (complex I) up 1.70 7.14 × 10−7 Oxidative phosphorylation/electron transport chain ATP synthesis coupled electron transport
PDXK Homo sapiens pyridoxal (pyridoxine, vitamin B6) kinase up 1.32 3.27 × 10−6 Vitamin B6/dopamine metabolism Pyridoxine biosynthetic process
SRGPA3 Homo sapiens SLIT-ROBO Rho GTPase activating protein 3 up 1.23 5.65 × 10−6 Axon guidance/signaling by Rho GTPases Signal transduction
TRAPPC4 Homo sapiens trafficking protein particle complex 4 down 1.69 5.8 × 10−6 Vesicle tethering and fusion ER to Golgi vesiclemediated transport

KEGG = Kyoto Encyclopedia of Genes and Genomes; NADH = reduced nicotinamide adenine dinucleotide; ATP = adenosine triphosphate; SLIT-ROBO = SLIT-roundabout; GTPase = guanosine triphosphatase; ER = endoplasmic reticulum.

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