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. Author manuscript; available in PMC: 2014 May 27.
Published in final edited form as: Circ Res. 2013 Feb 15;112(4):721–741. doi: 10.1161/CIRCRESAHA.111.247940

Figure 9. Integrated regulation of ion transport by pyridine nucleotides.

Figure 9

Hypothetical scheme showing the regulation of plasma membrane and intracellular ion channels by NAD(P)(H) and their products, NAADP+, adenosine diphosphate ribose (ADPR), and cyclic ADPR. The scheme shows all ion transport systems that have been shown to be regulated by pyridine nucleotides. Individual cells may or may not express the entire complement of ion channels shown in the figure. cADPR indicates cyclic adenosine diphosphate ribose; NBD, nucleotide-binding domain; and TPC, two-pore channel. (Illustration: Ben Smith.)