Table 3.
Summary of the combinations of coatings and biomolecules which have been investigated for improving the interaction of electrodes and neural cells.
| Application | Coating | Biomolecule | Reference |
|---|---|---|---|
| Cell attachment | PEDOT | DCDPGYIGSR and DEDEDYFQRYLI | Green et al. (2010b) |
| PEDOT | DCDPGYIGSR and DEDEDYFQRYLI | Green et al. (2009) | |
| PEDOT | Fibronectin fragments DCDPGYIGSR | Cui and Martin (2003) | |
| PPy | Fibronectin fragments Nonapeptide CDPGYIGSR | Cui et al. (2001b) | |
| CNT | Collagen type IV | Nguyen-Vu et al. (2006) | |
| Anti-inflammatory | PPy | HA | Collier et al. (2000) |
| PPy | Dexamethasone | Wadhwa et al. (2006) | |
| PEDOT electrodeposited on PLGA nanofibers | Dexamethasone | Abidian et al. (2006) | |
| Polyterthiophene | Dexamethasone phosphate | Stevenson et al. (2010) | |
| Alginate hydrogel loaded with Poly(lactic-co-glicolide)(PLGA) nanoparticles | Dexamethasone | Kim and Martin (2006) | |
| Nitrocellulose | αMSH | Zhong and Bellamkonda (2005),2007 | |
| Silicon | αMSH | He et al. (2007) | |
| Multiwalled CNTs | Dexamethasone | Luo et al. (2011a) | |
| Growth factors | Methylcellulose | PDGF-BB and IGF-1 | Wells et al. (1997) |
| Poly (ethylene-co-vinyl acetate) (EVA) (EVA rods) | NGF, NT-3, BDNF and GDNF, | Bloch et al. (2001), Barras et al. (2002), Fine et al. (2002) | |
| Agarose | NGF and Laminin | Yu and Bellamkonda (2003) | |
| Collagen | NT-3 | Houweling et al. (1998) | |
| PEG and PEG-PLA | NT-3 | Burdick et al. (2006), Piantino et al. (2006) | |
| Agarose | BNDF | Jain et al. (2006) | |
| Fibrin | Heparin binding delivery system (HBDS) and NT-3 | Taylor and Sakiyama-Elbert (2006) | |
| PPy | Laminin fragments RNIAEIIKDI (p20) | Stauffer and Cui (2006) | |
| PEG-PLA | NGF, | Winter et al. (2007) | |
| pHEMA-lysine | NGF, | Jhaveri et al. (2008) | |
| Fibrin | NGF | Lee et al. (2003) | |
| Multiwalled CNT | NGF | Matsumoto et al. (2007) |
HA, hyaluronic acid; αMSH, α-melanocyte stimulating hormone; NGF, nerve growth factor; PDGF-BB, platelet derived growth factor-BB; IGF-1, insulin-like growth factor-1; BDNF, brain derived neurotrophic factor; GDNF, glial cell-derived neurotrophic factor; NT-3 – neurotrophin 3; HBDS, heparin binding delivery system; PEG, poly(ethylene glycol); PEG-PLA, poly(ethylene glycol)-poly(lactic acid); and CNT, carbon nanotube.