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. Author manuscript; available in PMC: 2014 May 27.
Published in final edited form as: Cancer Res. 2008 Nov 15;68(22):9497–9502. doi: 10.1158/0008-5472.CAN-08-2085

Figure 3.

Figure 3

Ku80-mutant small intestines exhibit increased p21 levels that are dependent upon p53 in response to 8 Gy γ-radiation as shown by Q-PCR. Lanes 1–3: no IR. Lanes 4–7: 8 Gy. Lanes 1 & 4: Ku80+/+ p53+/+. Lanes 2 & 5: Ku80+/− p53+/+. Lane 3 & 6: ku80−/− p53+/+. Lane 7: Ku80+/+p53−/−. The average of three samples is shown for each cohort. Statistics (student t test) comparing lanes 4 & 6 are above lane 6 and comparing lanes 6 & 7 are above lane 7.