Figure 7.

Sprouting of horizontal cell axons in response to photoreceptor degeneration. Horizontal cell axon morphology was assessed at indicated ages using an antibody against neurofilament 200 in WT (A–F) and Aipl1^−/− (G–L) retina. Arrow points to sprouting of horizontal cell axonal branches in the Aipl1^−/− retina at P14 (G). Sprouting of horizontal cell axons was extensive at P30 to P60 ([I, J], arrow). At P100 to P150, arrowhead indicates axonal complexes that are sparse with uneven and large gaps in NF-200 staining pattern (K, L). Scale bar: 20 μm.