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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Alzheimers Dis. 2014;39(4):759–773. doi: 10.3233/JAD-131166

Fig. 1.

Fig. 1

Tissue processing and sampling. A) 1.5 cm thick coronal block at the level of the genu of the corpus callosum was cut through the left hemibrain in most subjects. B) The middle frontal gyrus (box) was dissected from the block and cut into 50 μm thick sections. C) The gray matter mantle was outlined in StereoInvestigator and a random sampling grid was generated, with 5 sites per section.